Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to produce more growth hormone (GH). It is FDA-approved primarily for reducing visceral fat in HIV-associated lipodystrophy, but it also has potential benefits for fat loss, muscle preservation, and cognitive health.

1. Stimulates Natural Growth Hormone (GH) Production
   • Binds to GHRH receptors in the pituitary, increasing endogenous GH release.
   • Promotes IGF-1 (Insulin-like Growth Factor-1) production, which aids in tissue repair, muscle growth, and fat metabolism.

1. Reduces Visceral Fat & Enhances Fat Metabolism
   • Specifically targets abdominal visceral fat, making it effective for fat loss.
   • Improves lipid profiles, lowering triglycerides and enhancing metabolic health.

1. Preserves Muscle Mass
   • Prevents muscle loss while reducing fat, unlike other weight loss methods.
   • Helps with muscle recovery and strength maintenance.

1. Cognitive & Neuroprotective Effects
   • Studies suggest it may improve cognitive function and memory, particularly in aging individuals.
   • May have potential benefits for Alzheimer’s prevention.

1. Improves Insulin Sensitivity & Metabolic Health
   • Enhances glucose metabolism, reducing the risk of insulin resistance and diabetes.
   • May be beneficial for those with metabolic disorders.

✅ Significant Visceral Fat Reduction – Clinically proven to reduce belly fat, especially in those with lipodystrophy.
✅ Increases Natural Growth Hormone Levels – Without suppressing endogenous GH production.
✅ Preserves Muscle & Enhances Recovery – Supports muscle retention and repair.
✅ Potential Cognitive Benefits – May improve memory and brain function in aging individuals.
✅ Improves Metabolic Health – Enhances lipid profiles and insulin sensitivity.